Visit stand M50 to learn more about Solastemis, Gattefossé's new active ingredient from plant origin. This powerful ingredient is said to protect the skin against UV rays, and responds to the growing needs of consumers concerned about the health of their skin. A physical barrier between the inside and the outside, Gattefossé notes that the skin is one of the most responsive organs to external aggressions, particularly to UV light. UV strongly impacts the nuclei of skin cells, the DNA, leading to structural and functional alterations of the different layers of the skin.

According to Gattefossé, Solastemis acts at the heart of the epidermis mechanics, by protecting the DNA of keratinocytes from lesions induced by UVA radiation and by boosting endogenous DNA repair system. It preserves the stem cells of the epidermis ensuring proper homeostasis for the skin’s first line of defense. It also offers a shield for the dermal extra-cellular matrix by protecting key macromolecules (collagen, elastin) from degradation induced by solar exposure.

“One of the primary strengths of Solastemis is its ability to provide a biological protection against UVA-induced epidermal damage. UVA radiation is commonly associated with photoaging, based on its ability to penetrate human skin deeper than UVB radiation, deep down to the dermis. However, UVA radiation strongly affects the epidermis, notably by affecting the self-renewal potential of keratinocyte stem-cells, thereby compromising the constant renewal of the epidermis. Solastemis has been shown in vitro to reduce oxidative stress within epidermal keratinocytes and to improve endogenous DNA repair system, both of which contribute to the preservation of epidermal self-renewal potential. Interestingly, it provides significant protection to the dermis as well making it a perfect solution for global photoprotection at epidermal and dermal level,” explained Boris Vogelgesang, R&D director cosmetic actives.

Tested versus placebo on a panel of 33 caucasian women (37-55 years-old), Solastemis confirmed its capacity to reduce symptoms of photoaging. Results show a significant reduction of crow’s feet wrinkles combined with an overall improved skin smoothness. Skin tone is embellished for a more lucent, even, and healthier complexion.

Solastemis's factive molecules are extracted from Sechium edule (also known as chayote or christophene), a fruit cultivated and manually harvested following zero-waste principles, in Salazie, on La Réunion island. Long-lasting relationships with local producers and harvesters guarantee a perfect traceability and quality, from field to factory, according to Gattefossé.

More info: Gattefossé, www.gattefosse.com